Baltimore Ravens vs Kansas City Chiefs picks, predictions, odds: Who wins NFL Week 1 game?

The Baltimore Ravens and Kansas City Chiefs play Thursday, Sept. 5, at Arrowhead Stadium in the first game on the NFL Week 1 schedule.

Which team will win the Thursday Night Football game?

Check out these NFL Week 1 picks and NFL Week 1 predictions for the football game, which can be seen at 5:20 p.m. MST on NBC (stream on Peacock).

The Chiefs are a 3-point favorite over the Ravens in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.

Kansas City Chiefs Vs Baltimore Ravens Photos

Kansas City is -155 on the moneyline, while Baltimore is +130.

The over/under (point total) is set at 46.5 points.

NFL Week 1 picks: Ravens vs Chiefs | Packers vs Eagles | Steelers vs Falcons | Cardinals vs Bills | Titans vs Bears | Patriots vs Bengals | Texans vs Colts | Jaguars vs Dolphins | Panthers vs Saints | Vikings vs Giants | Raiders vs Chargers | Broncos vs Seahawks | Cowboys vs Browns | Commanders vs. Buccaneers | Rams vs Lions | Jets vs 49ers | The Arizona Republic’s predictions

Jeremy Cluff writes: “The Chiefs open the season as the 2025 Super Bowl favorite, but the Ravens aren’t far behind in the odds. The environment in Kansas City should be a raucous one. The Chiefs will win a thriller.”

It writes: “We don’t see anyone stopping Mahomes & Co., especially at Arrowhead. The two-time MVP is 36-11 at home in his career. He’s also 15-4 in September and 5-2 on Thursdays. After beating the Ravens by a touchdown on the road in their most recent matchup, we like the Chiefs to win by at least a field goal here and cover the spread. Kansas City is mostly healthy and a well-oiled machine at this point, whereas Baltimore may struggle with its new-look offensive line and defensively without Macdonald. Mahomes is 4-1 against the Ravens (including the postseason), so look for him and the defending Super Bowl champs to kick off the season with a win.”

The site’s formula predicts that the Ravens will win the NFL Week 1 game against the Chiefs.

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Sayre Bedinger writes: “This should be a fun matchup with a lot of fireworks and two of the toughest defenses in the NFL.”

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Bill Speros writes: “The Chiefs celebrate their second-straight Super Bowl title. Expect Taylor Swift to be in attendance along with a full house in Kansas City for this AFC Championship Game rematch. The Chiefs opened the NFL season at home last year and lost to the Lions. The Ravens have seen multiple departures in free agency and on their coaching staff. But John Harbaugh has four months to prepare for this game. He’s 12-4 in Week 1 and is getting points. Lamar Jackson pocketed a 5-year, $260 million contract this offseason. He’ll be fully healthy, something that’s always an issue in the postseason. And he’s 11-2 ATS as a starter as an underdog.”

It writes: “According to our analysis, the Chiefs are more likely to beat the Ravens in the NFL game at GEHA Field at Arrowhead Stadium on Thursday.”